Rabbit anti N-SMase Activation Associated Factor
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Catalog numberX2354P
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Price:
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Size10MinibLots
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CategoryPrimary Antibodies
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Long descriptionNovel adaptor protein which mediates the activation of sphingomyelinase by receptors such as tumor necrosis factor receptor type 1 and CD40 and subsequent apoptosis in cardiomyocytes. Inhibition of this factor may provide a novel intervention point for reducing ischemia/reperfusion injury.
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Antibody come fromSynthetic peptide derived from human GPCR94.
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Antigen Immunoaffiinity Purification
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ClonePolyclonal
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Antigen antibody binding interactionRabbit anti N-SMase Activation Associated Factor Antibody
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Antibody is raised inRabbit
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Antibody s reacts withHuman
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationWestern Blot
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Antibody s suited forAntibody can be used for Western blotting (1-5µg/ml). Optimal concentration should be evaluated by serial dilutions.
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Storage-20ºC
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Relevant referencesCommuni, D, et al. Identification of a novel human ADP receptor coupled to Gi.;_x000B_J. Biol. Chem. 276:41479-41485(2001).
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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AboutRabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolNSMAF
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Short nameRabbit anti N-SMase Activation Associated Factor
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Techniqueactivation, Rabbit, anti, antibody to
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HostRabbit, Rabbits
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Isotypenot specified
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Labelunlabeled
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Alternative nameproduction species: rabbit antibody to N-SMase Activation Associated Factor
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Alternative techniquerabbit-anti, antibodies
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Gene info
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Identity
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Gene
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Long gene nameneutral sphingomyelinase activation associated factor
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Synonyms gene name
- neutral sphingomyelinase (N-SMase) activation associated factor
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-11-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BEACH domain containing
- GRAM domain containing
- WD repeat domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data