Rabbit anti Lysophospholipid Phosphatase (LPP) 1/1A

• Catalog number
  X1527P
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. It catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG), and is a pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. It is a major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. It may control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. Its down-regulation may contribute to the development of colon adenocarcinoma.
• Antibody come from
  Full length recombinant human Ssu72 protein
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide.
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti Lysophospholipid Phosphatase (LPP) 1/1A Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot
• Antibody s suited for
  Antibody can be used for Western blot (1-5 µg/ml). Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1. St-Pierre, B., et al. 'Conserved and specific functions of mammalian ssu72' Nucleic Acids Res. 2005, 33, 464-477_x000B__x000B_2. Krishnamurthy, S., et al. 'Ssu72 is an RNA polymerase II CTD phosphatase' Mol. Cell 2004, 14, 387-394_x000B__x000B_3. Steinmetz, EJ., Brow, DA. 'Ssu72 protein mediates both poly(A)-coupled and poly(A)-independent termination of RNA polymerase II transcription' Mol Cell Biol 2003, 23, 6339-6349
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Lysophospholipid   Phosphatase   LPP   1/1A  
• Gene symbol
  LPP-AS1, LPP, LPP-AS2
• Short name
  Rabbit anti Lysophospholipid Phosphatase (LPP) 1/1A
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to Lysophospholipid Phosphatase (LIM domain containing preferred translocation partner in lipoma) 1/1A
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  LIM domain containing preferred translocation partner in lipoma, LPP and IDBG-69427 and ENSG00000145012 and 4026, zinc ion binding, nuclei, Lpp and IDBG-149949 and ENSMUSG00000033306 and 210126, LPP and IDBG-634548 and ENSBTAG00000044001 and 524132

Gene info

• Identity
  HGNC:40346
• Gene
  LPP-AS1
• Long gene name
  LPP antisense RNA 1
• Synonyms gene name
  • LPP antisense RNA 1 (non-protein coding)
• Locus
  3q28
• Discovery year
  2011-07-28
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000156388

Gene info

• Identity
  HGNC:6679
• Gene
  LPP
• Long gene name
  LIM domain containing preferred translocation partner in lipoma
• Synonyms gene name
  • LIM domain-containing preferred translocation partner in lipoma
• Synonyms name
  • lipoma preferred partner gene
• GenBank acession
  • AL833171
• Locus
  3q27.3-q28
• Discovery year
  1996-07-19
• Entrez gene record
  4026
• Pubmed identfication
  • 8812423
• RefSeq identity
  • NM_005578
• Classification
  • Zyxin family
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000156387

Gene info

• Identity
  HGNC:27952
• Gene
  LPP-AS2
• Long gene name
  LPP antisense RNA 2
• Synonyms gene name
  • LPP antisense RNA 2 (non-protein coding)
• Synonyms
  • MYCLo-5
  • MYCLo-6
• GenBank acession
  • BC042414
• Locus
  3q27.3
• Discovery year
  2011-07-28
• Entrez gene record
  339929
• Pubmed identfication
  • 12477932
  • 25663692
• RefSeq identity
  • NR_036497
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000185119

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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