Rabbit anti Integrin antibody Alpha X (Antigen CD11C (P150) antibody Alpha Polypeptide) (ITGAX)
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Catalog numberX2175P
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Price:
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Size50 μg
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CategoryPrimary Antibodies
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Long descriptionIntegrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis
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Antibody come fromcytoplasmic domain of human
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Other descriptionPhosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
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ClonePolyclonal
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Antigen antibody binding interactionRabbit anti Integrin antibody Alpha X (Antigen CD11C (P150) antibody Alpha Polypeptide) (ITGAX) Antibody
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Antibody is raised inRabbit
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Antibody s reacts withHuman
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationImmunohistochemistry-Paraffin
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Antibody s suited forOptimal concentration should be evaluated by serial dilutions. ( WrkConcMin: 10 µg/ml)
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StorageLong term: -70ºC; Short term: +4ºC
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Relevant references1. Schillaci, R., et al, ÔClinical relevance of ErbB-2/HER2 nuclear expression in breast cancer.Õ BMC Cancer, 2012; 12: 74._x000B_2. Martin-Castillo, B., et al. Ô Basal/HER2 breast carcinomas.Õ Cell Cycle, Jan 2013; 12(2): 225-245._x000B_3. Lam, L., et al. ÔChallenges in the clinical utility of the serum test for HER2 ECD.Õ Biochim Biophys Acta, 2012: 1826(1): 199-208_x000B_4. Rexer, B. and Arteaga, C. ÔIntrinsic and Acquired Resistance to HER2-Targeted Therapies in HER2 Gene-Amplified Breast Cancer: Mechanisms and Clinical Implications.Õ Crit Rev Oncog, 2012: 17(1): 1-16._x000B_5. Hudis, Clifford. Ô Trastuzumab-Mechanism of Action and Use in Clinical Practice.Õ The New England Journal of Medicine, 2007: 357: 39-51.
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionThe Rabbit anti Integrin antibody Alpha X (Antigen CD11C (P150) antibody Alpha Polypeptide) (ITGAX) is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antigens are peptides or recombinant or native dependent on the production method.
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PropertiesIf you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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AboutRabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolITGAX, PIK3R4, ABL1, ANPEP, CHAF1A
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Short nameRabbit anti Integrin antibody Alpha X (Antigen CD11C (P150) antibody Alpha Polypeptide) (ITGAX)
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TechniqueAntibody, antigen, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for, antigenes
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HostRabbit, Rabbits
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Isotypenot specified
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Labelunlabeled
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Alternative nameproduction species: rabbit antibody to Integrin (antibody to-) a X (protein CD11C (P150) (antibody to-) a multipeptide) (integrin, alpha X (complement component 3 receptor 4 subunit))
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Alternative techniqueantibodies, antigenes, rabbit-anti
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Alternative to gene targetintegrin, alpha X (complement component 3 receptor 4 subunit), CD11C and SLEB6, ITGAX and IDBG-28212 and ENSG00000140678 and 3687, metal ion binding, Cell surfaces, Itgax and IDBG-210550 and ENSMUSG00000030789 and 16411
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Gene info
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Identity
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Gene
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Long gene nameintegrin subunit alpha X
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Synonyms gene
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Synonyms gene name
- integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
- integrin, alpha X (complement component 3 receptor 4 subunit)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-08-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Integrin alpha subunits
- Complement system regulators and receptors
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephosphoinositide-3-kinase regulatory subunit 4
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Synonyms gene name
- phosphoinositide-3-kinase, regulatory subunit 4
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Armadillo like helical domain containing
- WD repeat domain containing
- PIK3C3 complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameABL proto-oncogene 1, non-receptor tyrosine kinase
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Synonyms gene
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Synonyms gene name
- v-abl Abelson murine leukemia viral oncogene homolog 1
- c-abl oncogene 1, receptor tyrosine kinase
- c-abl oncogene 1, non-receptor tyrosine kinase
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Synonyms
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Abl family tyrosine kinases
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namealanyl aminopeptidase, membrane
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Synonyms gene
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Synonyms gene name
- alanyl (membrane) aminopeptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-02-28
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Entrez gene record
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Pubmed identfication
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Classification
- M1 metallopeptidases
- CD molecules
- Aminopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namechromatin assembly factor 1 subunit A
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Synonyms gene name
- chromatin assembly factor 1, subunit A (p150)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data