Rabbit anti Glucagon

• Catalog number
  MUB0706S
• Price
  Please ask
• Size
  0,25 mL

• Category
  Primary Antibodies
• Long description
  Glucagon is produced by the A-cells of the pancreatic islets. It occurs also in endocrine cells of the gut and in neurons in the brain. Glucagon is a common constituent of endocrine pancreatic tumours and of rectal carcinoids, such tumours may give rise to the so called glucagonoma syndrome.
• Antibody come from
  This polyclonal antibody is a Rabbit polyclonal antibody. The Rabbits were immunized with pancreatic glucagon.
• Other description
  Each vial contains 250ul Rabbit polyclonal antiSerum including 0.09% sodium azide
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti Glucagon Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human,Rat
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  The antibody stains cytoplasma localized glucagon conjugated to BSA.
• Research interest
  Hormones
• Application
  Immunocytochemistry,Immunohistochemistry (frozen),Immunohistochemistry (paraffin)
• Antibody s suited for
  This antibody is suitable for immunocytochemistry and immunohistochemistry on frozen and paraffin-embedded (without pretreatment) tissue sections. Recommended antibody dilution: 1:50. Dilute immediately before use with PBS or Tris.
• Storage
  Store undiluted antibody at 2-8°C (until expiry date). For prolonged storage: store aliquots at -20°C.
• Relevant references
  Bottcher, G. et al. –Pancreas 9,4(1989)469-474.
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This product contains sodium azide. To prevent formation of toxic vapors, do not mix with strong acidic solutions. To prevent formation of potentially explosive metallic azides in metal plumbing, always wash into drain with copious quantities of water. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Glucagon gene and the glucagon like peptide or GLP1 gene are peptide hormones, produced by alpha cells of the pancreas to raise the concentration of glucose in the blood as opposite of insulin, which lowers the glucose. Anti human glucagon and glp1 antibodies are used to study diabetes.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Glucagon  
• Gene symbol
  GLP2R, GCG, GCGR
• Short name
  Rabbit anti Glucagon
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to Glucagon
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:4325
• Gene
  GLP2R
• Long gene name
  glucagon like peptide 2 receptor
• Synonyms gene name
  • glucagon-like peptide 2 receptor
• GenBank acession
  • AF105367
• Locus
  17p13.1
• Discovery year
  1999-02-23
• Entrez gene record
  9340
• Pubmed identfication
  • 9990065
• Classification
  • Glucagon receptor family
• VEGA ID
  OTTHUMG00000130269

Gene info

• Identity
  HGNC:4191
• Gene
  GCG
• Long gene name
  glucagon
• Synonyms
  • GLP1
  • GLP2
  • GRPP
  • GLP-1
• Synonyms name
  • glicentin-related polypeptide
  • glucagon-like peptide 1
  • glucagon-like peptide 2
  • preproglucagon
• Locus
  2q24.2
• Discovery year
  2001-06-22
• Entrez gene record
  2641
• Pubmed identfication
  • 2753890
  • 3725587
• RefSeq identity
  • NM_002054
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000153892

Gene info

• Identity
  HGNC:4192
• Gene
  GCGR
• Long gene name
  glucagon receptor
• Synonyms
  • GGR
• GenBank acession
  • U03469
  • L20316
• Locus
  17q25.3
• Discovery year
  1994-03-04
• Entrez gene record
  2642
• Pubmed identfication
  • 8020989
• RefSeq identity
  • NM_000160
• Classification
  • Glucagon receptor family
• VEGA ID
  OTTHUMG00000177914

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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