Rabbit anti Focal Adhesion Kinase 1 (PTK2 antibody FAK1)
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Catalog number
X2108P
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Price
Please ask
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Size
50 μg
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Category
Primary Antibodies
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Long description
Focal adhesion kinase (FAK) is a non-receptor protein-tyrosine kinase that is involved in signaling pathways involved in cell motility, proliferation, and apoptosis. FAK is activated by tyrosine phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. FAK plays a potential role in oncogenic transformation resulting in increased kinase activity.
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Antibody come from
3rd cytoplasmic domain of human
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Other description
Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
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Clone
Polyclonal
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Antigen antibody binding interaction
Rabbit anti Focal Adhesion Kinase 1 (PTK2 antibody FAK1) Antibody
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Antibody is raised in
Rabbit
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Immunohistochemistry
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Antibody s suited for
Optimal concentration should be evaluated by serial dilutions.( WrkConcMin: 2.5 µg/ml)
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Storage
Long term: -70ºC; Short term: +4ºC
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Relevant references
no information yet
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Rabbit anti Focal Adhesion Kinase 1 (PTK2 antibody FAK1). This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Properties
If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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French translation
anticorps
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Gene target
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Gene symbol
PTK2
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Short name
Rabbit anti Focal Adhesion Kinase 1 (PTK2 antibody FAK1)
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Technique
Antibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
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Host
Rabbit, Rabbits
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Isotype
not specified
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Label
unlabeled
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Alternative name
production species: rabbit antibody to Focal Adhesion phosphorylation catalyst 1 (PTK2 protein tyrosine kinase 2 (antibody to-) FAK1)
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Alternative technique
antibodies, rabbit-anti
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Alternative to gene target
PTK2 protein tyrosine kinase 2, FADK and FAK and FAK1 and FRNK and p125FAK and pp125FAK and PPP1R71, PTK2 and IDBG-37147 and ENSG00000169398 and 5747, transferase activity, nuclei, Ptk2 and IDBG-148322 and ENSMUSG00000022607 and 14083, PTK2 and IDBG-643924 and ENSBTAG00000009578 and 506270
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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