Rabbit anti ERK/MAPK (Thr202/Tyr204)

• Catalog number
  X1670P
• Price
  Please ask
• Size
  10MinibLots

• Category
  Primary Antibodies
• Long description
  Extracellular-Signal Regulated Kinase/Mitogen-Activated Protein Kinase (ERK/MAPK) is an integral component of cellular signaling during mitogenesis and differentiation of mitotic cells and also is thought to play a key role in learning and memory. The activity of this kinase is regulated by dual phosphorylation at Thr202 and Tyr204.
• Antibody come from
  Fusion protein from the N-terminus of rabbit renal Na+/Ca2+ exchanger
• Other description
  Lyophilized (See usage for reconstitution). Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti ERK/MAPK (Thr202/Tyr204) Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human, Mouse, Rat, Xenopus
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot, Dot Blot
• Antibody s suited for
  Antibody can be used for Westen blot (1:1000 dilution). Optimal concentration should be evaluated by serial dilutions. This lyophilized antibody can be stored at -20¼C and is stable for at least 2 years. The antibody should be reconstituted in 50µl PBS before use. After reconstitution the antibody should be aliquoted and stored at -20C.
• Storage
  -80ºC
• Relevant references
  1. Bano D, Young KW, Guerin CJ, Lefeuvre R, Rothwell NJ, Naldini L, Rizzuto R, Carafoli E, Nicotera P (2005) Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity. Cell 120:275-285._x000B__x000B_2. Choi DW (2005) Neurodegeneration: cellular defences destroyed. Nature 433:696-698._x000B__x000B_3. Hagihara H, Yoshikawa Y, Ohga Y, Takenaka C, Murata KY, Taniguchi S, Takaki M (2005) Na+/Ca2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes. Am J Physiol Heart Circ Physiol 288:H1699-H1707._x000B__x000B_4. Matsuoka S, Nicoll DA, Reilly RF, Hilgemann DW, Philipson KD (1993) Initial localization of regulatory regions of the cardiac sarcolemmal Na+/Ca2+ exchanger. Proc Natl Acad Sci USA 90:3870-3874.
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  ERK/MAPK   Thr202/Tyr204  
• Gene symbol
  EPHB2, MAPK1
• Short name
  Rabbit anti ERK/MAPK (Thr202/Tyr204)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to ERK/MAPK (Thr202/Tyr204)
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:3393
• Gene
  EPHB2
• Long gene name
  EPH receptor B2
• Synonyms gene
  • DRT
  • ERK
  • EPHT3
• Synonyms gene name
  • EphB2
• Synonyms
  • Hek5
  • Tyro5
• GenBank acession
  • AF025304
• Locus
  1p36.12
• Discovery year
  1995-05-09
• Entrez gene record
  2048
• Pubmed identfication
  • 1648701
• RefSeq identity
  • NM_017449
• Classification
  • EPH receptors
  • MicroRNA protein coding host genes
  • Sterile alpha motif domain containing
• VEGA ID
  OTTHUMG00000002881
• Locus Specific Databases
  • LRG_780

Gene info

• Identity
  HGNC:6871
• Gene
  MAPK1
• Long gene name
  mitogen-activated protein kinase 1
• Synonyms gene
  • PRKM2
  • PRKM1
• Synonyms
  • ERK
  • ERK2
  • p41mapk
  • MAPK2
• GenBank acession
  • M84489
• Locus
  22q11.22
• Discovery year
  1993-11-05
• Entrez gene record
  5594
• Classification
  • Mitogen-activated protein kinases
• VEGA ID
  OTTHUMG00000030508
• Locus Specific Databases
  • LRG_786

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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