Rabbit anti ERBB-4 Receptor Protein Tyrosine Kinase (ERBB4)

• Catalog number
  X2266P
• Price
  Please ask
• Size
  50 μg

• Category
  Primary Antibodies
• Long description
  Specifically binds and is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. Interaction with these factors induces cell differentiation. Not activated by EGF, TGF-A, and amphiregulin. Expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. Lower levels in thymus, lung, salivary gland, and pancreas. Isoform JM-A and isoform JM-B are expressed in cerebellum, but only the isoform JM-B is expressed in the heart.
• Antibody come from
  C-terminal domain of human
• Other description
  Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti ERBB-4 Receptor Protein Tyrosine Kinase (ERBB4) Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Immunohistochemistry
• Antibody s suited for
  Antibody can be used for immunohistochemistry on formalin-fixed, paraffin-embedded tissues (20 µg/ml). Optimal concentration should be evaluated by serial dilutions.
• Storage
  Long term: -70ºC; Short term: +4ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  ERBB-4   Receptor   Protein   Tyrosine   Kinase   ERBB4  
• Gene symbol
  ERBB4, EGFR, MIR1302-4, PIRC18, PIRC16, SNORD114-4, MIR941-4, IGKV2OR2-4
• Short name
  Rabbit anti ERBB-4 Receptor Protein Tyrosine Kinase (ERBB4)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to ERBB-4 Receptor Protein Tyrosine phosphorylation catalyst (v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian))
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), ALS19 and HER4 and p180erbB4, ERBB4 and IDBG-79992 and ENSG00000178568 and 2066, transferase activity, nuclei, Erbb4 and IDBG-164078 and ENSMUSG00000062209 and 13869, ERBB4 and IDBG-643612 and ENSBTAG00000012647 and

Gene info

• Identity
  HGNC:3432
• Gene
  ERBB4
• Long gene name
  erb-b2 receptor tyrosine kinase 4
• Synonyms gene name
  • v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
• Synonyms
  • ALS19
  • HER4
• Synonyms name
  • human epidermal growth factor receptor 4
• GenBank acession
  • L07868
• Locus
  2q34
• Discovery year
  1995-09-07
• Entrez gene record
  2066
• Pubmed identfication
  • 7700649
  • 17018285
• RefSeq identity
  • NM_001042599
• Classification
  • Erb-b2 receptor tyrosine kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133012

Gene info

• Identity
  HGNC:3236
• Gene
  EGFR
• Long gene name
  epidermal growth factor receptor
• Synonyms gene
  • ERBB
• Synonyms gene name
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
• Synonyms
  • ERBB1
  • ERRP
• Synonyms name
  • erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian)
  • erb-b2 receptor tyrosine kinase 1
• Locus
  7p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  1956
• Pubmed identfication
  • 1505215
• RefSeq identity
  • NM_005228
• Classification
  • Erb-b2 receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000023661
• Locus Specific Databases
  • LRG_304

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37520
• Gene
  PIRC16
• Long gene name
  piwi-interacting RNA cluster 16
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313849
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33687
• Gene
  MIR941-4
• Long gene name
  microRNA 941-4
• Synonyms gene
  • MIRN941-4
• Synonyms
  • hsa-mir-941-4
• Locus
  20q13.33
• Discovery year
  2007-10-24
• Entrez gene record
  100126330
• RefSeq identity
  • NR_040032
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:5809
• Gene
  IGKV2OR2-4
• Long gene name
  immunoglobulin kappa variable 2/OR2-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-4
  • immunoglobulin kappa variable 2/OR2-4 pseudogene
• Synonyms
  • IGKV2/OR2-4
• GenBank acession
  • X51883
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28858
• Pubmed identfication
  • 2111145
• Classification
  • Immunoglobulin kappa (IGK) orphons

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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