NUMB - Blocking Peptide
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Catalog numberX2291B
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PricePlease ask
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Size50 μg
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CategoryProteins & Peptides
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Long descriptionNUMB is implicated in the control of cell fate decisions during development. It interacts with EPS15, LNX and NOTCH1, and may interact with DUOXA1. It interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis.
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Antibody come fromSynthetic peptide derived from the human Lass1 protein.
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide.
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Clonenot specified
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Antigen antibody binding interactionNUMB - Blocking Peptide
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Antibody is raised insee techfile
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Antibody s reacts withsee techfile
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationWestern Blot
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Antibody s suited forAntibody can be used for Western blotting (1:400 starting dilution). Other uses not yet tested. Only reacts with human Lass1 protein. Does not cross react with other species. Optimal concentration should be evaluated by serial dilutions.
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Storage-20ºC
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Relevant references[1] Lee S.-J.; Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure.; Proc. Natl. Acad. Sci. U.S.A. 88:4250-4254(1991)._x000B__x000B_[2] Jiang J.C., Kirchman P.A., Zagulski M., Hunt J., Jazwinski S.M.; Homologs of the yeast longevity gene LAG1 in Caenorhabditis elegans and human.; Genome Res. 8:1259-1272(1998)._x000B__x000B_[3] Grimwood J., et al.; The DNA sequence and biology of human chromosome 19.;_x000B_Nature 428:529-535(2004)._x000B__x000B_[4] The MGC Project Team; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).; Genome Res. 14:2121-2127(2004).
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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TestYou can block the antibody by the specific target amino acid sequence of peptide.
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Propertiesblocking peptide
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DescriptionPeptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
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Gene target
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Gene symbolNUMB, NUMBL
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Short nameNUMB - Blocking Peptide
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Techniqueblocking peptide, Blocking, peptide, blocking peptides, nordc made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
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Isotypenot specified
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Labelunlabeled
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Alternative nameNUMB - inhibiting short protein sequence
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Alternative techniquecontrol, peptides
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Gene info
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Identity
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Gene
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Long gene nameNUMB endocytic adaptor protein
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Synonyms gene
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Synonyms gene name
- numb (Drosophila) homolog
- chromosome 14 open reading frame 41
- numb homolog (Drosophila)
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GenBank acession
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Locus
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Discovery year1999-03-12
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNUMB like endocytic adaptor protein
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Synonyms gene name
- numb (Drosophila) homolog-like
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
