Mouse anti Proximal Nephrogenic Renal Antigen antibody cln PN-15 (66.4.C2)

• Catalog number
  X1234M
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  This antibody reacts with a glycoprotein of 200 kDa present in proximal renal tubules. The antigen is a carbohydrate in nature and retained in formalin fixed paraffin embedded tissues. Other normal tissues that display the antigen include breast, parathyroid glands and epididymis. Among renal carcinomas, 93% of primary and 84% of metastatic carcinomas are positive for this antigen. Relatively few other tumor types are positive: breast cancers, teratocarcinomas and parathyroid adenomas.
• Antibody come from
  Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with renal cortical tissue extract and mouse myeloma cells
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
• Clone
  66.4.C2
• Antigen antibody binding interaction
  Mouse anti Proximal Nephrogenic Renal Antigen antibody cln PN-15 (66.4.C2) Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Immunohistochemistry (Paraffin Sections)
• Antibody s suited for
  This antibody can be used for the differential diagnosis of carcinomas by Western blotting and immunohistochemistry on frozen and paraffin-embedded tissues. Protease digestion prior to antibody incubation enhances staining of tissue sections. Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1. Yoshida, S.O. and Imam, A., 'Monoclonal antibody to a proximal nephrogenic renal antigen: immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal cell carcinomas.' Cancer Res. 1989, 49, 1802-1809._x000B__x000B_2. Piron, A., et al. 'In vitro demonstration of a mitogenic activity in renal tissue extracts during regenerative hyperplasia.' Am. J. Physiol. 1998, 274, F348-F357.
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antigens are peptides or recombinant or native dependent on the production method.
• Properties
  If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Proximal   Nephrogenic   Renal   cln   PN-15  
• Gene symbol
  PIRC66, PIRC71, PIRC75, PIRC67, PIRC72, PIRC68, PIRC62, PIRC70, PIRC76, PIRC77
• Short name
  Mouse anti Proximal Nephrogenic Renal Antigen antibody cln PN-15 (66 4 C2)
• Technique
  Antibody, antigen, Mouse, anti, antibody to, antibodies against human proteins, antibodies for, antigenes, mouses
• Host
  mouse
• Isotype
  IgG2b
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to Proximal Nephrogenic Renal protein (antibody to-) cln PN-15 (66.4.complement component 2)
• Alternative technique
  antibodies, antigenes, murine
• Alternative to gene target
  complement component 2, ARMD14 and CO2, C2 and IDBG-124824 and ENSG00000166278 and 101928623,717, protein binding, Extracellular, C2 and IDBG-174547 and ENSMUSG00000024371 and 12263, C2 and IDBG-633680 and ENSBTAG00000007450 and 515440

Gene info

• Identity
  HGNC:37570
• Gene
  PIRC66
• Long gene name
  piwi-interacting RNA cluster 66
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313865
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37575
• Gene
  PIRC71
• Long gene name
  piwi-interacting RNA cluster 71
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313818
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37579
• Gene
  PIRC75
• Long gene name
  piwi-interacting RNA cluster 75
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313919
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37571
• Gene
  PIRC67
• Long gene name
  piwi-interacting RNA cluster 67
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313817
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37576
• Gene
  PIRC72
• Long gene name
  piwi-interacting RNA cluster 72
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313867
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37572
• Gene
  PIRC68
• Long gene name
  piwi-interacting RNA cluster 68
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313931
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37566
• Gene
  PIRC62
• Long gene name
  piwi-interacting RNA cluster 62
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313816
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37574
• Gene
  PIRC70
• Long gene name
  piwi-interacting RNA cluster 70
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313866
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37580
• Gene
  PIRC76
• Long gene name
  piwi-interacting RNA cluster 76
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313796
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37581
• Gene
  PIRC77
• Long gene name
  piwi-interacting RNA cluster 77
• Locus
  15
• Discovery year
  2009-11-05
• Entrez gene record
  100313868
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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