Mouse anti p16 - ink4a
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Catalog numberC170M
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PricePlease ask
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Size100 μg
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CategoryPrimary Antibodies
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Long descriptionThe immunogen for the anti-human p16 was a recombinant full length p16 protein recognizing a 16kDa protein. The p16ink4a tumor suppressor protein shows no cross reactivity with the closely related inhibitors such as p15ink4b and p18ink4c. p16ink4a is a specific inhibitor of cdk4/cdk6, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including melanoma and lung carcinoma.
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Antibody come fromA recombinant full length p16 protein recognizing a 16kDa protein
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
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CloneDCS50.1
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Antigen antibody binding interactionMouse anti p16 - ink4a Antibody
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Antibody is raised inMouse
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Antibody s reacts withHuman
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationWestern Blot, Immunoprecipitation, Immunohistochemistry
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Antibody s suited forApplications: Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6)
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Storage-20ºC
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Relevant references1) J. Lukas et.al (1995) Nature., 375,503-506 _x000B__x000B_2) L. Aagaard et.al. (1995), Intl. J. of Cancer 61(1) 115-120
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolCDKN2A
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Short nameMouse anti p16 - ink4a
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TechniqueMouse, anti, antibody to, mouses
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Hostmouse
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IsotypeIgG1
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Labelunlabeled
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SpeciesMouse, Mouses
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Alternative nameMouse antibody to p16 - ink4a
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Alternative techniquemurine, antibodies
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Gene info
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Identity
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Gene
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Long gene namecyclin dependent kinase inhibitor 2A
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Synonyms gene
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Synonyms gene name
- cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-05-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data