Mouse anti p15 - ink4b
-
Catalog numberC110M
-
PricePlease ask
-
Size100 μg
-
-
CategoryPrimary Antibodies
-
Long descriptionThe immunogen for the anti-human p15 was a his-tagged recombinant full length p15 protein recognizing a 15kDa protein. The p15ink4b tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16ink4a and p19ink4d. p15ink4b is a specific inhibitor of cdk4/cdk6, and is periodically expressed during cell cycle.
-
Antibody come fromA his-tagged recombinant full length p15 protein recognizing a 15kDa protein
-
Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
-
CloneDCS114.1
-
Antigen antibody binding interactionMouse anti p15 - ink4b Antibody
-
Antibody is raised inMouse
-
Antibody s reacts withHuman
-
Antibody s reacts with these speciesThis antibody doesn't cross react with other species
-
Antibody s specificityNo Data Available
-
ApplicationWestern Blot, Immunoprecipitation, Immunohistochemistry (paraffin)
-
Antibody s suited forApplications: 1-5 ug /ml for Western Blot, Immunohistochemistry, Immunoprecipitation (co-precipitates cdk4/cdk6)
-
Storage-20ºC
-
Relevant references1) C. Sherr, et.al. (1995) Gene & Dev..9, 1149-1163 _x000B__x000B_2) Sakellariou, S., et al. 'Immunohistochemical Expression of P15 (INK4B) and SMAD4 in Advanced Gastric Cancer.' Anticancer Research (2008), 28, 1079-1083
-
Protein numbersee ncbi
-
WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin nameMus musculus
-
Gene target
-
Gene symbolCDKN2B
-
Short nameMouse anti p15 - ink4b
-
TechniqueMouse, anti, antibody to, mouses
-
Hostmouse
-
IsotypeIgG1
-
Labelunlabeled
-
SpeciesMouse, Mouses
-
Alternative nameMouse antibody to p15 - ink4b
-
Alternative techniquemurine, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namecyclin dependent kinase inhibitor 2B
-
Synonyms gene name
- cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1995-06-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data