Mouse anti Interleukin-10 (Biotinylated) (IL-10)
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Catalog numberX1912M
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PricePlease ask
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Size100 μg
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CategoryPrimary Antibodies
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Long descriptionInhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.Defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.
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Antibody come fromHybridoma produced by the fusion of splenocytes from BALB/c mice immunized with recombinant rat IL-4 protein and NSO mouse myeloma cells.
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
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Clone945A5A10
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Antigen antibody binding interactionMouse anti Interleukin-10 (Biotinylated) (IL-10) Antibody
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Antibody is raised inMouse
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Antibody s reacts withHuman
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationELISA as detection antibody_x000B__x000B_
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Antibody s suited forAntibody can be used for ELISA as a coating antibody (1.25 µg/ml). Optimal concentration should be evaluated by serial dilutions.
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Storage-20ºC
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Relevant references1. Wildbaum, G., et al 'Plasmid DNA encoding IFN-gamma-Inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis.' J. Immunol. 2002;168 (11):5885-5892._x000B__x000B_2. Sanchez, R., 'T9 glioma cells expressing membrane-macrophage colony stimulating fact or produce CD4+T cell-associated protective immunity against T9 intracranial gliomas and systemic immunity against different syngeneic gliomas.' Cellular Immunology 2002; 215(1):1-11._x000B__x000B_3. Salomon, I., 'Targeting the function of INF-gamma inducible protein 10 suppresses ongoing adjuvant arthritis.' J. Immunol. 2002; 169:2685-2693.
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolIL10, SNORD115-10, PIRC49, SNORD116-10, IL36G, IL25, IGKV2OR2-10
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Short nameMouse anti Interleukin-10 (Biotinylated) (IL-10)
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TechniqueMouse, anti, antibody to, mouses
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Hostmouse
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IsotypeIgG1
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LabelBiotin
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SpeciesMouse, Mouses
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Alternative nameMouse antibody to Interleukin-10 (Biotinylated) (Interleukin-10)
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Alternative techniquemurine, antibodies
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 10
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-10-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-10
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 49
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 116-10
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 25
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Synonyms gene
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Synonyms gene name
- interleukin 17E
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-01-26
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Pubmed identfication
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 2/OR2-10 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 2/OR2-10
- immunoglobulin kappa variable 2/OR2-10 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa (IGK) orphons
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
