BACE-1

Alternative names

BACE1, Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE, KIAA1149, HSPC104
Product Type

Recombinant Protein
NCBI

NP_036236
Concentration

0.5mg/ml (determined by BCA assay)
Formulation

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
SDSPAGE Comment and Pic

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain{ATGP3917-SDSPAGE.jpg}
Purity

> 90% by SDS - PAGE
Applications

SDS-PAGE,Enzyme Activity
Antigen Species

Human
UniProt No

P56817
Gene Category

Enzymes & Proteases,Neuroscience
Molecular Weight

49.2kDa (442aa)
Tag

His-Tag
Expression System

Baculovirus
Storage and shipping

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data sheet
Note

This product is available in other size; please contact us for more details

Gene target

BACE-1
Gene symbol

BACE1, BACE1-AS, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1, MIR16-1
Short name

BACE-1
Alternative name

BACE-1

Identity

HGNC:933
Gene

BACE1
Long gene name

beta-secretase 1
Synonyms gene
- BACE
Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
GenBank acession
- AF190725
Locus

11q23.3
Discovery year

1999-10-29
Entrez gene record

23621
Pubmed identfication
- 10531052
Classification
- Peptidase family A1
VEGA ID

OTTHUMG00000160636

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081