ZEB1 Antibody

• Catalog number
  R31092
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ZEB1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the ZEB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This ZEB1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P37275
• Purity
  Antigen affinity
• Description
  Zinc Finger E Box-Binding Homeobox 1, also called TCF8, NIL2A or DELTA-EF1, is a protein that in humans is encoded by the ZEB1 gene. Fluorescence in situ hybridization localized the ZEB1 gene to chromosome 10p11.2. Krafchak et al.(2005) demonstrated a complex(core plus secondary) binding site for TCF8 in the promoter of the COL4A3 gene, mutant in Alport syndrome and which encodes collagen type IV alpha-3. They detected expression of TCF8 in cornea. Nishimura et al.(2006) found that delta-Ef1 was upregulated during differentiation in a mouse smooth muscle cell(SMC) line.
• Immunogen
  An amino acid sequence from the N-terminus of human Zinc Finger E Box-Binding Homeobox 1 (KDDECESDAENEQNHD) was used as the immunogen for this ZEB1 antibody.
• Storage
  After reconstitution, the ZEB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ZEB1  
• Gene symbol
  ZEB1-AS1, ZEB1
• Short name
  Anti-ZEB1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to ZEB1
• Alternative technique
  antibodies
• Alternative to gene target
  zinc finger E-box binding homeobox 1, AREB6 and BZP and DELTAEF1 and FECD6 and NIL2A and PPCD3 and TCF8 and ZFHEP and ZFHX1A, ZEB1 and IDBG-66941 and ENSG00000148516 and 100996668,6935, E-box binding, nuclei, Zeb1 and IDBG-127909 and ENSMUSG00000024238 and 21417, ZEB1 and IDBG-638511 and ENSBTAG00000020053 and 535183

Gene info

• Identity
  HGNC:42354
• Gene
  ZEB1-AS1
• Long gene name
  ZEB1 antisense RNA 1
• Synonyms gene name
  • ZEB1 antisense RNA 1 (non-protein coding)
• Locus
  10p11.22
• Discovery year
  2011-06-30
• Entrez gene record
  220930
• Pubmed identfication
  • 26617942
  • 28075045
  • 27829995
• RefSeq identity
  • NR_024284
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000017905

Gene info

• Identity
  HGNC:11642
• Gene
  ZEB1
• Long gene name
  zinc finger E-box binding homeobox 1
• Synonyms gene
  • TCF8
  • PPCD3
• Synonyms gene name
  • transcription factor 8 (represses interleukin 2 expression)
  • posterior polymorphous corneal dystrophy 3
• Synonyms
  • BZP
  • ZEB
  • AREB6
  • NIL-2-A
  • Zfhep
  • Zfhx1a
  • FECD6
• GenBank acession
  • AK091478
• Locus
  10p11.22
• Discovery year
  1991-12-17
• Entrez gene record
  6935
• Pubmed identfication
  • 1427828
  • 1840704
  • 15384081
  • 16252232
• RefSeq identity
  • NM_030751
• Classification
  • ZF class homeoboxes and pseudogenes
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000017907

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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