XRCC1 Antibody

• Catalog number
  F49231-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  XRCC1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, FACS, IF, ELISA
• Recommended dilutions
  Immunofluorescence: 1:25,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the XRCC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This XRCC1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P18887
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
• Immunogen
  A portion of amino acids 407-435 from the human protein was used as the immunogen for this XRCC1 antibody.
• Storage
  Aliquot the XRCC1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  XRCC1  
• Gene symbol
  XRCC1
• Short name
  Anti-XRCC1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to XRCC1
• Alternative technique
  antibodies
• Alternative to gene target
  X-ray repair complementing defective repair in Chinese hamster cells 1, RCC, XRCC1 and IDBG-55268 and ENSG00000073050 and 7515, protein binding, nuclei, Xrcc1 and IDBG-155000 and ENSMUSG00000051768 and 22594, XRCC1 and IDBG-639023 and ENSBTAG00000016268 and 616905

Gene info

• Identity
  HGNC:12828
• Gene
  XRCC1
• Long gene name
  X-ray repair cross complementing 1
• Synonyms gene
  • RCC
• Synonyms gene name
  • X-ray repair complementing defective repair in Chinese hamster cells 1
• GenBank acession
  • M36089
• Locus
  19q13.31
• Discovery year
  2001-06-22
• Entrez gene record
  7515
• Pubmed identfication
  • 2247054
• RefSeq identity
  • NM_006297
• VEGA ID
  OTTHUMG00000182699
• Locus Specific Databases
  • LRG_784

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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