VE Cadherin Antibody (CDH5)

• Catalog number
  F48144-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  VE Cadherin (CDH5)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the VE Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This VE Cadherin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P33151
• Purity
  Antigen affinity
• Description
  CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
• Immunogen
  A portion of amino acids 106-134 from the human protein was used as the immunogen for this VE Cadherin antibody.
• Storage
  Aliquot the VE Cadherin antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cadherin   CDH5  
• Gene symbol
  CDH5
• Short name
  Anti-VE Cadherin (CDH5)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to VE Cadherin (CDH5)
• Alternative technique
  antibodies
• Alternative to gene target
  cadherin 5, type 2 (vascular endothelium), 7B4 and CD144, CDH5 and IDBG-34871 and ENSG00000179776 and 1003, ion channel binding, Cell surfaces, Cdh5 and IDBG-185038 and ENSMUSG00000031871 and 12562, BT.64659 and IDBG-633039 and ENSBTAG00000007421 and 414735

Gene info

• Identity
  HGNC:1764
• Gene
  CDH5
• Long gene name
  cadherin 5
• Synonyms gene name
  • cadherin 5, type 2, VE-cadherin (vascular epithelium)
  • cadherin 5, type 2 (vascular endothelium)
• Synonyms
  • 7B4
  • CD144
• Synonyms name
  • VE-cadherin
• GenBank acession
  • X79981
• Locus
  16q21
• Discovery year
  1992-11-20
• Entrez gene record
  1003
• Pubmed identfication
  • 2059658
• RefSeq identity
  • NM_001795
• Classification
  • Type II classical cadherins
  • CD molecules
• VEGA ID
  OTTHUMG00000137495

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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