VANGL2 Antibody

• Catalog number
  F53408-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  VANGL2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:2000
• Notes
  Titration of the VANGL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This VANGL2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9ULK5
• Purity
  Antigen affinity
• Description
  Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
• Immunogen
  This VANGL2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-410 amino acids from human VANGL2.
• Storage
  Aliquot the VANGL2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  VANGL2  
• Gene symbol
  VANGL2
• Short name
  Anti-VANGL2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to VANGL2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15511
• Gene
  VANGL2
• Long gene name
  VANGL planar cell polarity protein 2
• Synonyms gene name
  • vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila)
  • vang-like 2 (van gogh, Drosophila)
• Synonyms
  • KIAA1215
  • LTAP
  • LPP1
  • STBM
  • STB1
  • STBM1
  • MGC119403
  • MGC119404
• Synonyms name
  • vang, van gogh-like 2
  • loop-tail-associated protein
  • strabismus
• GenBank acession
  • AB033041
• Locus
  1q23.2
• Discovery year
  2001-04-06
• Entrez gene record
  57216
• Pubmed identfication
  • 11431695
• RefSeq identity
  • NM_020335
• VEGA ID
  OTTHUMG00000033122

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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