USP16 Antibody

• Catalog number
  F40114-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  USP16
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IHC, WB, ELISA
• Recommended dilutions
  IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
• Notes
  Titration of the USP16 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This USP16 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9Y5T5
• Purity
  Purified
• Description
  Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
• Immunogen
  A portion of amino acids 1-30 from the human protein was used as the immunogen for this USP16 antibody.
• Storage
  Aliquot the USP16 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  USP16  
• Gene symbol
  USP16, USP21
• Short name
  Anti-USP16
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to USP16
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12614
• Gene
  USP16
• Long gene name
  ubiquitin specific peptidase 16
• Synonyms gene name
  • ubiquitin specific protease 16
• Synonyms
  • Ubp-M
• GenBank acession
  • AF126736
• Locus
  21q21
• Discovery year
  1999-07-09
• Pubmed identfication
  • 12838346
• Classification
  • Ubiquitin specific peptidases
• VEGA ID
  OTTHUMG00000078802

Gene info

• Identity
  HGNC:12620
• Gene
  USP21
• Long gene name
  ubiquitin specific peptidase 21
• Synonyms gene
  • USP23
• Synonyms gene name
  • ubiquitin specific protease 21
• Synonyms
  • USP16
• GenBank acession
  • AF177758
• Locus
  1q23.3
• Discovery year
  2000-06-08
• Entrez gene record
  27005
• Pubmed identfication
  • 12838346
  • 10799498
• Classification
  • Ubiquitin specific peptidases
• VEGA ID
  OTTHUMG00000033154

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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