Uroplakin 3A Antibody

• Catalog number
  V2295-20UG
• Price
  Please ask
• Size
  20 ug

• Category
  Antibody
• Concentration
  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Uroplakin 3A
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens). Other species not known. ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, FACS, IF
• Recommended dilutions
  FACS: 0.5-1ug/million cells,IF: 1-2ug/ml,WB: 0.5-1ug/ml
• Notes
  The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
• Added buffer
  1X Phosphate Buffered Saline (PBS), pH 7.4
• Intented use
  This Uroplakin 3A antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  7380
• Purity
  Purified by protein A Affinity Chromatography
• Description
  Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.
• Immunogen
  A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A was used as the immunogen for this antibody.
• Storage
  Store the Uroplakin 3A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Localization
  Cell surface
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Uroplakin  
• Gene symbol
  UPK3A
• Short name
  Anti-Uroplakin 3A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Uroplakin 3A
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12580
• Gene
  UPK3A
• Long gene name
  uroplakin 3A
• Synonyms gene
  • UPK3
• Synonyms gene name
  • uroplakin 3
• GenBank acession
  • AB010637
• Locus
  22q13.31
• Discovery year
  1992-07-31
• Entrez gene record
  7380
• Pubmed identfication
  • 9818021
• RefSeq identity
  • NM_006953
• VEGA ID
  OTTHUMG00000151339

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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