Urokinase Antibody (UPA, Plau)
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Catalog number
F51093-0.08ML
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Price
Please ask
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Size
0.08 ml
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Category
Antibody
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Concentration
In 1X PBS, pH 7.4, with 0.09% sodium azide
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Form
Purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
Urokinase (UPA, Plau)
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB, IHC, FACS, ELISA
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Recommended dilutions
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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Notes
Titration of the Urokinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented use
This Urokinase antibodyis to be used only for research purposes and not for diagnostics..
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Uniprot
P00749
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Purity
Purified
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Description
PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin. The protein is found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A. Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain. The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis. Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.
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Immunogen
A portion of amino acids 60-90 from the human protein was used as the immunogen for this Urokinase antibody.
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Storage
Aliquot the Urokinase antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
PRAP1, PLAU
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Short name
Anti-Urokinase (UPA, Plau)
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit Ig
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Alternative name
Antibodies to Urokinase (UPA, Plau)
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Alternative technique
antibodies
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Alternative to gene target
plasminogen activator, urokinase, ATF and BDPLT5 and QPD and u-PA and UPA and URK, PLAU and IDBG-78889 and ENSG00000122861 and 5328, protein binding, Extracellular, Plau and IDBG-136606 and ENSMUSG00000021822 and 18792, PLAU and IDBG-630603 and ENSBTAG00000005947 and 281408
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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