TXNL2 Antibody / GLRX3

• Catalog number
  R32534
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TXNL2 / GLRX3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Added buffer
  Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
• Intented use
  This TXNL2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O76003
• Purity
  Antigen affinity
• Description
  Glutaredoxin-3, also called Thioredoxin-like protein 2 or TXNL2, is a protein that in humans is encoded by the GLRX3 gene. This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
• Immunogen
  Amino acids L89-S177 from the human protein were used as the immunogen for the TXNL2 antibody.
• Storage
  After reconstitution, the TXNL2 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TXNL2   GLRX3  
• Gene symbol
  GLRX3
• Short name
  Anti- TXNL2 / GLRX3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TXNL2 / GLRX3
• Alternative technique
  antibodies
• Alternative to gene target
  glutaredoxin 3, GLRX4 and GRX3 and GRX4 and PICOT and TXNL2 and TXNL3, GLRX3 and IDBG-93235 and ENSG00000108010 and 10539, iron-sulfur cluster binding, nuclei, Glrx3 and IDBG-211431 and ENSMUSG00000031068 and 30926, GLRX3 and IDBG-641075 and ENSBTAG00000005027 and 511528

Gene info

• Identity
  HGNC:15987
• Gene
  GLRX3
• Long gene name
  glutaredoxin 3
• Synonyms gene
  • TXNL2
• Synonyms gene name
  • thioredoxin-like 2
• Synonyms
  • PICOT
  • bA500G10.4
  • GRX3
  • GLRX4
  • GRX4
• Synonyms name
  • glutaredoxin 4
• GenBank acession
  • AJ010841
• Locus
  10q26.3
• Discovery year
  2001-06-27
• Entrez gene record
  10539
• Pubmed identfication
  • 10636891
  • 11124703
• RefSeq identity
  • NM_006541
• Classification
  • Glutaredoxin domain containing
• VEGA ID
  OTTHUMG00000019267

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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