Tubulin beta 3 Antibody / TUBB3

• Catalog number
  R32611
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Tubulin beta 3 / TUBB3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
• Notes
  Optimal dilution of the Beta III Tubulin antibody should be determined by the researcher.
• Added buffer
  Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
• Intented use
  This antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q13509
• Purity
  Antigen affinity
• Description
  Tubulin beta-3 chain is a protein that in humans is encoded by the TUBB3 gene. This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
• Immunogen
  Amino acids 383-412 (EQFTAMFRRKAFLHWYTGEGMDEMEFTEAE-human) were used as the immunogen for the Beta III Tubulin antibody.
• Storage
  After reconstitution, the Beta III Tubulin antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Tubulin   beta   TUBB3  
• Gene symbol
  TUBB3
• Short name
  Anti- Tubulin beta 3 / TUBB3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Tubulin beta 3 / TUBB3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20772
• Gene
  TUBB3
• Long gene name
  tubulin beta 3 class III
• Synonyms gene
  • FEOM3
• Synonyms gene name
  • tubulin, beta 3
  • fibrosis of extraocular muscles, congenital, 3
• Synonyms
  • beta-4
  • CFEOM3
  • CFEOM3A
• Synonyms name
  • class III beta-tubulin
• GenBank acession
  • BC000748
• Locus
  16q24.3
• Discovery year
  2004-11-22
• Entrez gene record
  10381
• Pubmed identfication
  • 9473684
  • 8098743
  • 20074521
• RefSeq identity
  • NM_006086
• Classification
  • Tubulins
• VEGA ID
  OTTHUMG00000138985

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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