TRIB2 Antibody

• Catalog number
  R32292
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TRIB2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the TRIB2 antibody should be determined by the researcher.
• Intented use
  This TRIB2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q92519
• Purity
  Antigen affinity
• Description
  Tribbles homolog 2 is a protein that in humans is encoded by the TRIB2 gene. This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBP alpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
• Immunogen
  Amino acids DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSD of human TRIB2 were used as the immunogen for the TRIB2 antibody.
• Storage
  After reconstitution, the TRIB2 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, membranous
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRIB2  
• Gene symbol
  TRIB2
• Short name
  Anti-TRIB2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TRIB2
• Alternative technique
  antibodies
• Alternative to gene target
  tribbles homolog 2 (Drosophila), TRIB2 and IDBG-30297 and ENSG00000071575 and 28951, transferase activity, Cytoplasm, Trib2 and IDBG-129207 and ENSMUSG00000020601 and 217410, TRIB2 and IDBG-637840 and ENSBTAG00000016045 and 352960

Gene info

• Identity
  HGNC:30809
• Gene
  TRIB2
• Long gene name
  tribbles pseudokinase 2
• Synonyms gene name
  • tribbles homolog 2 (Drosophila)
• Synonyms
  • TRB2
  • GS3955
• GenBank acession
  • AY245544
• Locus
  2p24.3
• Discovery year
  2004-04-30
• Entrez gene record
  28951
• Pubmed identfication
  • 12736262
  • 17097562
  • 16715410
• RefSeq identity
  • NM_021643
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000090575

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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