TRAF6 Antibody

• Catalog number
  F47406-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TRAF6
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the TRAF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TRAF6 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9Y4K3
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported. [provided by RefSeq].
• Immunogen
  A portion of amino acids 314-343 from the human protein was used as the immunogen for this TRAF6 antibody.
• Storage
  Aliquot the TRAF6 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRAF6  
• Gene symbol
  TRAF6
• Short name
  Anti-TRAF6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TRAF6
• Alternative technique
  antibodies
• Alternative to gene target
  TNF receptor-associated factor 6, E3 ubiquitin protein ligase, MGC:3310 and RNF85, TRAF6 and IDBG-40102 and ENSG00000175104 and 7189, protein N-terminus binding, nuclei, Traf6 and IDBG-193222 and ENSMUSG00000027164 and 22034, TRAF6 and IDBG-636763 and ENSBTAG00000036009 and 539124

Gene info

• Identity
  HGNC:12036
• Gene
  TRAF6
• Long gene name
  TNF receptor associated factor 6
• Synonyms gene name
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase
• Synonyms
  • RNF85
• Locus
  11p12
• Discovery year
  1997-06-12
• Entrez gene record
  7189
• Pubmed identfication
  • 8837778
• RefSeq identity
  • NM_145803
• Classification
  • Ring finger proteins
  • TNF receptor associated factors
• VEGA ID
  OTTHUMG00000166391

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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