TRAF5 Antibody

• Catalog number
  R31274
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TRAF5
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the TRAF5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TRAF5 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O00463
• Purity
  Antigen affinity
• Description
  TNF receptor-associated factor 5, also known as RNF84, is a protein that in humans is encoded by the TRAF5 gene. The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor(TRAF) protein family. Fluorescence in situ hybridization confirmed the regional localization of human TRAF5 to chromosome 1q32.2-q32.3. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. It is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. It seems to be involved in apoptosis.
• Immunogen
  An amino acid sequence from the N-terminus of human TNF receptor-associated factor 5 (HRFCQHCILSLREL) was used as the immunogen for this TRAF5 antibody.
• Storage
  After reconstitution, the TRAF5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRAF5  
• Gene symbol
  TRAF5
• Short name
  Anti-TRAF5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TRAF5
• Alternative technique
  antibodies
• Alternative to gene target
  TNF receptor-associated factor 5, MGC:39780 and RNF84, TRAF5 and IDBG-106494 and ENSG00000082512 and 7188, thioesterase binding, Plasma membranes, Traf5 and IDBG-208924 and ENSMUSG00000026637 and, TRAF5 and IDBG-638230 and ENSBTAG00000012020 and 507234

Gene info

• Identity
  HGNC:12035
• Gene
  TRAF5
• Long gene name
  TNF receptor associated factor 5
• Synonyms
  • RNF84
• GenBank acession
  • AB000509
• Locus
  1q32.3
• Discovery year
  1997-02-03
• Entrez gene record
  7188
• Pubmed identfication
  • 9126477
• RefSeq identity
  • NM_004619
• Classification
  • TNF receptor associated factors
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000036997

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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