TLR1 Antibody

• Catalog number
  R31370
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TLR1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting points. Titration of the TLR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TLR1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q15399
• Purity
  Antigen affinity
• Description
  Toll-like receptor 1(TLR1), also called TIL or CD281 is a member of the Toll-like receptor family(TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.
• Immunogen
  An amino acid sequence from the C-terminus of human TLR1 (NLRAAINIKLTEQAKK) was used as the immunogen for this TLR1 antibody.
• Storage
  After reconstitution, the TLR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR1  
• Gene symbol
  TLR1
• Short name
  Anti-TLR1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TLR1
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 1, CD281 and rsc786 and TIL and TIL. LPRS5, TLR1 and IDBG-13627 and ENSG00000174125 and 7096, protein heterodimerization activity, Plasma membranes, Tlr1 and IDBG-165889 and ENSMUSG00000044827 and 21897

Gene info

• Identity
  HGNC:11847
• Gene
  TLR1
• Long gene name
  toll like receptor 1
• Synonyms gene name
  • toll-like receptor 1
• Synonyms
  • rsc786
  • KIAA0012
  • CD281
• GenBank acession
  • U88540
• Locus
  4p14
• Discovery year
  1998-06-25
• Entrez gene record
  7096
• Pubmed identfication
  • 9435236
  • 7584026
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000160413

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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