Titin Antibody / TTN

• Catalog number
  F53901-0.05ML
• Price
  Please ask
• Size
  0.05 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Titin / TTN
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IHC-P
• Recommended dilutions
  IHC (FFPE): 1:25
• Intented use
  This Titin antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  7273
• Uniprot
  Q8WZ42
• Purity
  Antigen affinity
• Description
  Titin is a key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.
• Immunogen
  A portion of amino acids 7169-7203 from the human protein was used as the immunogen for the Titin antibody.
• Storage
  Aliquot the Titin antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Titin   TTN  
• Gene symbol
  TTN-AS1, TTN
• Short name
  Anti- Titin / TTN
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Titin / TTN
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:44124
• Gene
  TTN-AS1
• Long gene name
  TTN antisense RNA 1
• Synonyms gene name
  • TTN antisense RNA 1 (non-protein coding)
• GenBank acession
  • BC041357
• Locus
  2q31.2
• Discovery year
  2012-06-23
• Entrez gene record
  100506866
• Pubmed identfication
  • 29101304
  • 31173403
• RefSeq identity
  • NR_038272
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000133536

Gene info

• Identity
  HGNC:12403
• Gene
  TTN
• Long gene name
  titin
• Synonyms gene
  • CMD1G
• Synonyms gene name
  • cardiomyopathy, dilated 1G (autosomal dominant)
• Synonyms
  • CMPD4
  • FLJ32040
  • TMD
  • CMH9
  • LGMD2J
  • MYLK5
• GenBank acession
  • X90568
• Locus
  2q31.2
• Discovery year
  1991-06-07
• Entrez gene record
  7273
• Pubmed identfication
  • 2129545
  • 10051295
• RefSeq identity
  • NM_133378
• Classification
  • Myosin light chain kinase family
  • I-set domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000154448
• Locus Specific Databases
  • FHC Mutation Database
  • TTN @ LOVD
  • Leiden Muscular Dystrophy pages
  • LRG_391

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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