TIGIT Antibody
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Catalog numberF53798-0.05ML
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Price:
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Size0.05 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenTIGIT
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 1:2000
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NotesTitration of the TIGIT antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis TIGIT antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ495A1
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PurityAntigen affinity
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DescriptionTIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
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ImmunogenA portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody.
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StorageAliquot the TIGIT antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTIGIT
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Short nameAnti-TIGIT
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to TIGIT
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Alternative techniqueantibodies
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Alternative to gene targetT cell immunoreceptor with Ig and ITIM domains, TIGIT and IDBG-50851 and ENSG00000181847 and 201633, protein binding, Cell surfaces, Tigit and IDBG-161101 and ENSMUSG00000071552 and 100043314, TIGIT and IDBG-632631 and ENSBTAG00000011921 and 100140801
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Gene info
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Identity
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Gene
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Long gene nameT cell immunoreceptor with Ig and ITIM domains
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Synonyms gene
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Synonyms gene name
- VSIG9, VSTM3
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-02-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- V-set domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data