Thrombopoietin Antibody / TPO
-
Catalog number
R32570
-
Price
Please ask
-
Size
0.1mg
-
-
Category
Antibody
-
Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
-
Form
Antigen affinity purified
-
Conjugation
Unconjugated
-
Clone
Polyclonal antibody
-
Recognised antigen
Thrombopoietin / TPO
-
Host animal
Rabbit (Oryctolagus cuniculus)
-
Clonality
Polyclonal (rabbit origin)
-
Species reactivity
Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
-
Tested applications
WB, ELISA (protein)
-
Recommended dilutions
Western blot: 0.5-1ug/ml,ELISA: 0.5-1ug/ml (human protein tested); request BSA-free format for coating
-
Added buffer
Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
-
Intented use
This Thrombopoietin antibodyis to be used only for research purposes and not for diagnostics..
-
Uniprot
P40225
-
Purity
Antigen affinity
-
Description
Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a protein that in humans is encoded by the THPO gene. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
-
Immunogen
Amino acids S22-R258 from the human protein were used as the immunogen for the Thrombopoietin antibody.
-
Storage
After reconstitution, the Thrombopoietin antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
-
Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
TPO, THPO
-
Short name
Anti- Thrombopoietin / TPO
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Rabbit IgG
-
Alternative name
Antibodies to Thrombopoietin / TPO
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
thyroid peroxidase
-
Synonyms
-
Locus
-
Discovery year
1986-01-01
-
Entrez gene record
-
RefSeq identity
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
thrombopoietin
-
Synonyms gene
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year
1994-11-04
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products