STT3A Antibody

• Catalog number
  F53973-0.2ML
• Price
  Please ask
• Size
  0.2 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  STT3A
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 1:1000-2000
• Intented use
  This STT3A antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  3703
• Uniprot
  P46977
• Purity
  Antigen affinity
• Description
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A is the catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.
• Immunogen
  A portion of amino acids 476-507 from the human protein was used as the immunogen for the STT3A antibody.
• Storage
  Aliquot the STT3A antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  STT3A  
• Gene symbol
  STT3A-AS1, STT3A
• Short name
  Anti- STT3A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to STT3A
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:44585
• Gene
  STT3A-AS1
• Long gene name
  STT3A antisense RNA 1
• GenBank acession
  • DB470444
  • DB453285
• Locus
  11q24.2
• Discovery year
  2012-11-19
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000165869

Gene info

• Identity
  HGNC:6172
• Gene
  STT3A
• Long gene name
  STT3 oligosaccharyltransferase complex catalytic subunit A
• Synonyms gene
  • ITM1
• Synonyms gene name
  • integral membrane protein 1
  • STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
  • STT3A, catalytic subunit of the oligosaccharyltransferase complex
• Synonyms
  • TMC
  • MGC9042
  • STT3-A
• Synonyms name
  • dolichyl-diphosphooligosaccharide protein glycotransferase
• GenBank acession
  • BC020965
• Locus
  11q24.2
• Discovery year
  1996-08-01
• Entrez gene record
  3703
• Pubmed identfication
  • 8941377
  • 8634329
  • 10234787
• RefSeq identity
  • NM_152713
• Classification
  • Oligosaccharyltransferase complex subunits
  • STT3 oligosaccharyltransferase catalytic subunits
• VEGA ID
  OTTHUMG00000165852

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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