SOX4 Antibody

• Catalog number
  R32196
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SOX4
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the SOX4 antibody should be determined by the researcher.
• Intented use
  This SOX4 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q06945
• Purity
  Antigen affinity
• Description
  Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). This protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
• Immunogen
  Amino acids MVQQTNNAENTEALLAGESSDSGAGLELGIA of human SOX4 were used as the immunogen for the SOX4 antibody.
• Storage
  After reconstitution, the SOX4 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Nuclear, cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SOX4  
• Gene symbol
  SOX4, CASC15
• Short name
  Anti-SOX4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to SOX4
• Alternative technique
  antibodies
• Alternative to gene target
  SRY (sex determining region Y)-box 4, EVI16, SOX4 and IDBG-64338 and ENSG00000124766 and 6659, protein heterodimerization activity, nuclei, Sox4 and IDBG-141246 and ENSMUSG00000076431 and 20677, SOX4 and IDBG-635807 and ENSBTAG00000046556 and

Gene info

• Identity
  HGNC:11200
• Gene
  SOX4
• Long gene name
  SRY-box transcription factor 4
• Synonyms gene name
  • SRY (sex determining region Y)-box 4
  • SRY-box 4
• GenBank acession
  • AF070669
• Locus
  6p22.3
• Discovery year
  1993-11-30
• Entrez gene record
  6659
• Pubmed identfication
  • 8268656
  • 9730625
• RefSeq identity
  • NM_003107
• Classification
  • SRY-box transcription factors
• VEGA ID
  OTTHUMG00000016101

Gene info

• Identity
  HGNC:28245
• Gene
  CASC15
• Long gene name
  cancer susceptibility 15
• Synonyms gene
  • LINC00340
• Synonyms gene name
  • long intergenic non-protein coding RNA 340
  • cancer susceptibility candidate 15 (non-protein coding)
  • cancer susceptibility 15 (non-protein coding)
• Synonyms
  • lnc-SOX4-1
• GenBank acession
  • AK026189
• Locus
  6p22.3
• Discovery year
  2011-08-10
• Entrez gene record
  401237
• Pubmed identfication
  • 26016895
  • 26100672
  • 28724437
• RefSeq identity
  • NR_015410
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000014345

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products