SOX2 Antibody
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Catalog numberF53133-0.08ML
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Price:
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS pH 7.4 with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenSOX2
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, ELISA
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Recommended dilutionsWestern blot: 1:1000
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NotesTitration of the SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis SOX2 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotP48432
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PurityAntigen affinity
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DescriptionTranscription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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ImmunogenThis SOX2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the N-terminal region of mouse Sox2.
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StorageAliquot the SOX2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSOX2, SOX2-OT
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Short nameAnti-SOX2
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to SOX2
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Alternative techniqueantibodies
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Alternative to gene targetSRY (sex determining region Y)-box 2, ANOP3 and MCOPS3, SOX2 and IDBG-66692 and ENSG00000181449 and 6657, protein heterodimerization activity, nuclei, Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674, SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383
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Gene info
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Identity
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Gene
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Long gene nameSRY-box transcription factor 2
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Synonyms gene name
- SRY (sex determining region Y)-box 2
- SRY-box 2
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GenBank acession
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Locus
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Discovery year1993-11-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SRY-box transcription factors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameSOX2 overlapping transcript
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Synonyms gene
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Synonyms gene name
- SOX2 overlapping transcript (non-protein coding)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-07-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Overlapping transcripts
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data