SOCS6 Antibody

• Catalog number
  F43534-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SOCS6
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
• Notes
  Titration of the SOCS6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This SOCS6 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O14544
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
• Immunogen
  A portion of amino acids 40-69 from the human protein was used as the immunogen for this SOCS6 antibody.
• Storage
  Aliquot the SOCS6 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SOCS6  
• Gene symbol
  SOCS6
• Short name
  Anti-SOCS6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to SOCS6
• Alternative technique
  antibodies
• Alternative to gene target
  suppressor of cytokine signaling 6, CIS-4 and CIS4 and HSPC060 and SOCS-4 and SOCS-6 and SOCS4 and SSI4 and STAI4 and STATI4, SOCS6 and IDBG-4847 and ENSG00000170677 and 9306, protein binding, Cell surfaces, Socs6 and IDBG-163115 and ENSMUSG00000056153 and 54607, SOCS6 and IDBG-643512 and ENSBTAG00000017412 and 615146

Gene info

• Identity
  HGNC:16833
• Gene
  SOCS6
• Long gene name
  suppressor of cytokine signaling 6
• Synonyms gene
  • SOCS4
• Synonyms gene name
  • suppressor of cytokine signaling 4
• Synonyms
  • CIS4
  • SSI4
  • HSPC060
  • STATI4
  • STAI4
  • Cish4
• GenBank acession
  • AB006968
• Locus
  18q22.2
• Discovery year
  2002-11-13
• Entrez gene record
  9306
• Pubmed identfication
  • 9344848
  • 11042152
• Classification
  • Suppressors of cytokine signaling
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000132816

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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