S100A8 Antibody / MRP8

• Catalog number
  R32039
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  S100A8 / MRP8
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the S100A8 antibody should be determined by the researcher.
• Intented use
  This S100A8 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P27005
• Purity
  Antigen affinity
• Description
  S100 calcium-binding protein A8 is a protein that in humans is encoded by the S100A8 gene. It is also known as Calgranulin A, MRP8 and Calprotectin L1L subunit. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
• Immunogen
  Amino acids 2-89 of mouse MRP8/S100A8 were used as the immunogen for the S100A8 antibody.
• Storage
  After reconstitution, the S100A8 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  S100A8   MRP8  
• Gene symbol
  S100A8, ABCC11, ABCC8
• Short name
  Anti-S100A8 / MRP8
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to S100A8 / MRP8
• Alternative technique
  antibodies
• Alternative to gene target
  S100 calcium binding protein A8, 60B8AG and CAGA and CFAG and CGLA and CP-10 and L1Ag and MA387 and MIF and MRP8 and NIF and P8, S100A8 and IDBG-102654 and ENSG00000143546 and 6279, RAGE receptor binding, nuclei, S100a8 and IDBG-168077 and ENSMUSG00000056054 and 20201, S100A8 and IDBG-632868 and ENSBTAG00000012640 and 616818

Gene info

• Identity
  HGNC:10498
• Gene
  S100A8
• Long gene name
  S100 calcium binding protein A8
• Synonyms gene
  • CAGA
  • CFAG
• Synonyms gene name
  • calgranulin A
  • cystic fibrosis antigen
• Synonyms
  • P8
  • MRP8
  • MRP-8
  • 60B8AG
  • CGLA
  • S100-A8
• Synonyms name
  • Migration inhibitory factor-related protein 8
  • Calprotectin L1L subunit
  • Leukocyte L1 complex light chain
• GenBank acession
  • BC005928
• Locus
  1q21.3
• Discovery year
  1989-05-19
• Entrez gene record
  6279
• RefSeq identity
  • NM_002964
• Classification
  • S100 calcium binding proteins
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000013124

Gene info

• Identity
  HGNC:14639
• Gene
  ABCC11
• Long gene name
  ATP binding cassette subfamily C member 11
• Synonyms gene name
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11
• Synonyms
  • MRP8
• GenBank acession
  • AF367202
• Locus
  16q12.1
• Discovery year
  2001-06-01
• Entrez gene record
  85320
• Pubmed identfication
  • 11483364
  • 11435397
• RefSeq identity
  • NM_032583
• Classification
  • ATP binding cassette subfamily C
• VEGA ID
  OTTHUMG00000133146

Gene info

• Identity
  HGNC:59
• Gene
  ABCC8
• Long gene name
  ATP binding cassette subfamily C member 8
• Synonyms gene
  • SUR
  • HRINS
• Synonyms gene name
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
• Synonyms
  • HI
  • PHHI
  • SUR1
  • MRP8
  • ABC36
  • HHF1
  • TNDM2
• Synonyms name
  • sulfonylurea receptor (hyperinsulinemia)
• GenBank acession
  • L78207
• Locus
  11p15.1
• Discovery year
  1995-01-10
• Entrez gene record
  6833
• Pubmed identfication
  • 7920639
  • 7716548
• RefSeq identity
  • NM_000352
• Classification
  • ATP binding cassette subfamily C
• VEGA ID
  OTTHUMG00000166316
• Locus Specific Databases
  • LRG_790

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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