RSK1 Antibody

• Catalog number
  R31163
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  RSK1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the RSK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This RSK1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q15418
• Purity
  Antigen affinity
• Description
  Ribosomal Protein S6 Kinase, 90-KD, 1, also called RSK1, is an enzyme that in humans is encoded by the RPS6KA1 gene. The RSK(ribosomal S6 kinase) family comprises growth factor-regulated serine/threonine kinases, known also as p90(RSK). Homologs exist in several species. By analysis of somatic cell hybrids, Moller et al.(1994) mapped the gene to chromosome 3. Bonni et al.(1999) characterized the mechanism by which the RAS-MAPK signaling pathway mediates growth factor-dependent cell survival. Inoue et al.(2007) demonstrated that p90RSK, the kinase immediately downstream from Mos-MAPK, directly targets Erp1 for CSF arrest in Xenopus oocytes.
• Immunogen
  An amino acid sequence from the C-terminus of human RSK1 (ILAQRRVRKLPSTTL) was used as the immunogen for this RSK1 antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the RSK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RSK1  
• Gene symbol
  RPS6KA1
• Short name
  Anti-RSK1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to RSK1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10430
• Gene
  RPS6KA1
• Long gene name
  ribosomal protein S6 kinase A1
• Synonyms gene name
  • ribosomal protein S6 kinase, 90kD, polypeptide 1
• Synonyms
  • RSK1
  • HU-1
  • p90Rsk
  • MAPKAPK1
• GenBank acession
  • BC014966
• Locus
  1p36.11
• Discovery year
  1994-07-11
• Entrez gene record
  6195
• Pubmed identfication
  • 8141249
  • 11049854
• RefSeq identity
  • NM_002953
• Classification
  • AGC family kinases
  • MAPK activated protein kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000004003

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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