ROBO1 Antibody

• Catalog number
  F53865-0.05ML
• Price
  Please ask
• Size
  0.05 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ROBO1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 1:1000-1:2000
• Intented use
  This ROBO1 antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  6091
• Uniprot
  Q9Y6N7
• Purity
  Antigen affinity
• Description
  Roundabout homolog 1 is the receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.
• Immunogen
  A portion of amino acids 1097-1130 from the human protein was used as the immunogen for the ROBO1 antibody.
• Storage
  Aliquot the ROBO1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ROBO1  
• Gene symbol
  ROBO1
• Short name
  Anti- ROBO1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to ROBO1
• Alternative technique
  antibodies
• Alternative to gene target
  roundabout, axon guidance receptor, homolog 1 (Drosophila), DUTT1 and SAX3, ROBO1 and IDBG-45469 and ENSG00000169855 and 6091, protein heterodimerization activity, Cell surfaces, Robo1 and IDBG-171072 and ENSMUSG00000022883 and 19876, ROBO1 and IDBG-630648 and ENSBTAG00000009851 and 536815

Gene info

• Identity
  HGNC:10249
• Gene
  ROBO1
• Long gene name
  roundabout guidance receptor 1
• Synonyms gene name
  • roundabout (axon guidance receptor, Drosophila) homolog 1
  • roundabout, axon guidance receptor, homolog 1 (Drosophila)
• Synonyms
  • DUTT1
  • FLJ21882
  • SAX3
• GenBank acession
  • AF040990
• Locus
  3p12.3
• Discovery year
  1998-03-26
• Entrez gene record
  6091
• Pubmed identfication
  • 9458045
  • 9608531
• RefSeq identity
  • NM_002941
• Classification
  • Fibronectin type III domain containing
  • Ig-like cell adhesion molecule family
  • I-set domain containing
• VEGA ID
  OTTHUMG00000158843

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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