RIAM Antibody

• Catalog number
  R31063
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  RIAM
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P, IHC-F, ICC
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,IHC (Frozen): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the RIAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This RIAM antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q7Z5R6
• Purity
  Antigen affinity
• Description
  RIAM (Rap1-interacting adaptor molecule), also called RARP1 and APBB1-Interacting Protein, is a protein that in humans is encoded by the APBB1IP gene. By genomic sequence analysis, Lafuente et al.(2004) mapped the gene to chromosome 10p12.1. Using promoter-reporter gene assays, Inagaki et al.(2003) found that RIAM suppressed transcription from AP1 and SRE sites, but not CRE sites, in all cell lines examined. The proline-rich regions of RIAM suppressed AP1 transactivation. Lafuente et al.(2004) found that the protein interacted with profilin and VASP, molecules that regulate actin dynamics, as well as with RAP1-GTP.
• Immunogen
  An amino acid sequence from the C-terminus of human Rap1-interacting adaptor molecule (EQDFMSDLMKALQKKRGNVS) was used as the immunogen for this RIAM antibody.
• Storage
  After reconstitution, the RIAM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RIAM  
• Gene symbol
  APBB1IP
• Short name
  Anti-RIAM
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to RIAM
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17379
• Gene
  APBB1IP
• Long gene name
  amyloid beta precursor protein binding family B member 1 interacting protein
• Synonyms gene name
  • amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
• Synonyms
  • INAG1
  • RIAM
• Synonyms name
  • Rap1-GTP-interacting adaptor molecule
• GenBank acession
  • AB085852
• Locus
  10p12.1
• Discovery year
  2003-03-07
• Entrez gene record
  54518
• Pubmed identfication
  • 9407065
• RefSeq identity
  • NM_019043
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000017841

MeSH Data

• Name
  Radioallergosorbent Test
• Concept
  Scope note: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
• Tree numbers
  • E01.370.225.812.735.830
  • E05.200.812.735.830
  • E05.478.566.380.810
  • E05.478.566.639.810
  • E05.478.594.760.830
  • E05.601.470.380.810
  • E05.601.470.639.810
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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