RELA Antibody NF-kB p65

• Catalog number
  R31513
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  RELA NF-kB p65
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the RELA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This RELA antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  4790
• Purity
  Antigen affinity
• Description
  Transcription factor p65, also known as NFKB3 or NF-kB p65, is a protein that in humans is encoded by the RELA gene. It is mapped to 11q13.1. RELA is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc, and it may play a role in inflammatory conditions of the peripheral nervous system. Phosphorylation and acetylation of RELA are crucial post-translational modifications required for NFkB activation. It has also been shown to modulate immune responses, and activation of the protein is positively associated with multiple types of cancer. In addition, RELA antagonizes TNFR1-JNK proliferative signals in epidermis and plays a nonredundant role in restraining epidermal growth.
• Immunogen
  Human partial recombinant protein (AA 99-551) was used as the immunogen for this RELA antibody.
• Storage
  After reconstitution, the RELA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RELA   NF-kB   p65  
• Gene symbol
  NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFATC2, NFYC, NFIL3
• Short name
  Anti-RELA NF-kB p65
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to RELA NF-kB p65
• Alternative technique
  antibodies
• Alternative to gene target
  v-rel reticuloendotheliosis viral oncogene homolog A (avian), NFKB3 and p65, RELA and IDBG-57543 and ENSG00000173039 and 5970, ankyrin repeat binding, nuclei, Rela and IDBG-132298 and ENSMUSG00000024927 and 19697, BT.26220 and IDBG-644222 and ENSBTAG00000013895 and 508233

Gene info

• Identity
  HGNC:29902
• Gene
  NFE4
• Long gene name
  nuclear factor, erythroid 4
• Synonyms
  • NF-E4
• Locus
  7q22.1
• Discovery year
  2013-08-23
• Entrez gene record
  58160
• Pubmed identfication
  • 11003662
• RefSeq identity
  • NR_166510
• VEGA ID
  OTTHUMG00000157208

Gene info

• Identity
  HGNC:7780
• Gene
  NFE2
• Long gene name
  nuclear factor, erythroid 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
• Synonyms
  • NF-E2
• GenBank acession
  • BC005044
• Locus
  12q13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4778
• Pubmed identfication
  • 8355703
• RefSeq identity
  • NM_006163
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000169761

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

Gene info

• Identity
  HGNC:6057
• Gene
  INA
• Long gene name
  internexin neuronal intermediate filament protein alpha
• Synonyms gene
  • NEF5
• Synonyms gene name
  • internexin neuronal intermediate filament protein, alpha
• Synonyms
  • NF-66
• GenBank acession
  • S78296
• Locus
  10q24.33
• Discovery year
  1999-03-24
• Entrez gene record
  9118
• Pubmed identfication
  • 7769995
• RefSeq identity
  • NM_032727
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000018986

Gene info

• Identity
  HGNC:29866
• Gene
  NFASC
• Long gene name
  neurofascin
• Synonyms gene name
  • neurofascin homolog (chicken)
• Synonyms
  • NRCAML
  • KIAA0756
  • FLJ46866
  • NF
• GenBank acession
  • AK027553
• Locus
  1q32.1
• Discovery year
  2005-11-22
• Entrez gene record
  23114
• Pubmed identfication
  • 1377696
  • 8672144
• RefSeq identity
  • NM_001005388
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000151697

Gene info

• Identity
  HGNC:7775
• Gene
  NFATC1
• Long gene name
  nuclear factor of activated T cells 1
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • nuclear factor of activated T-cells 1
• Synonyms
  • NF-ATC
  • NFATc
  • NFAT2
• GenBank acession
  • U08015
• Locus
  18q23
• Discovery year
  1994-11-16
• Entrez gene record
  4772
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_172390
• Classification
  • Nuclear factors of activated T-cells
  • IPT domain containing
• VEGA ID
  OTTHUMG00000132897

Gene info

• Identity
  HGNC:7776
• Gene
  NFATC2
• Long gene name
  nuclear factor of activated T cells 2
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • nuclear factor of activated T-cells 2
• Synonyms
  • NF-ATP
  • NFATp
  • NFAT1
• GenBank acession
  • U43342
  • U43341
• Locus
  20q13.2
• Discovery year
  1994-11-16
• Entrez gene record
  4773
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_012340
• Classification
  • IPT domain containing
  • Nuclear factors of activated T-cells
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000032747

Gene info

• Identity
  HGNC:7806
• Gene
  NFYC
• Long gene name
  nuclear transcription factor Y subunit gamma
• Synonyms gene name
  • nuclear transcription factor Y, gamma
• Synonyms
  • CBF-C
  • NF-YC
• GenBank acession
  • U78774
• Locus
  1p34.2
• Discovery year
  1996-10-26
• Entrez gene record
  4802
• Pubmed identfication
  • 8921405
  • 9249075
• RefSeq identity
  • NM_014223
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000007729

Gene info

• Identity
  HGNC:7787
• Gene
  NFIL3
• Long gene name
  nuclear factor, interleukin 3 regulated
• Synonyms gene
  • IL3BP1
• Synonyms gene name
  • interleukin-3 binding protein 1
• Synonyms
  • E4BP4
  • NFIL3A
  • NF-IL3A
• Synonyms name
  • E4 promoter-binding protein
  • adenovirus E4 promoter region binding protein
• GenBank acession
  • X64318
• Locus
  9q22.31
• Discovery year
  1995-02-13
• Entrez gene record
  4783
• Pubmed identfication
  • 7565758
  • 1620116
• RefSeq identity
  • NM_005384
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000020209

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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