RBPJ Antibody

• Catalog number
  F45603-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  RBPJ
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, IF, ELISA
• Recommended dilutions
  Western blot: 1:1000-2000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
• Notes
  Titration of the RBPJ antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This RBPJ antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q06330
• Purity
  Antigen affinity
• Description
  Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
• Immunogen
  A portion of amino acids 1-29 from the human protein was used as the immunogen for this RBPJ antibody.
• Storage
  Aliquot the RBPJ antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RBPJ  
• Gene symbol
  RBPJ
• Short name
  Anti-RBPJ
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to RBPJ
• Alternative technique
  antibodies
• Alternative to gene target
  recombination signal binding protein for immunoglobulin kappa J region, AOS3 and CBF1 and csl and IGKJRB and IGKJRB1 and KBF2 and RBP-J and RBPJK and RBPSUH and SUH, RBPJ and IDBG-12527 and ENSG00000168214 and 3516, protein N-terminus binding, nuclei, Rbpj and IDBG-164658 and ENSMUSG00000039191 and 19664, RBPJ and IDBG-641468 and ENSBTAG00000003602 and 767928

Gene info

• Identity
  HGNC:5724
• Gene
  RBPJ
• Long gene name
  recombination signal binding protein for immunoglobulin kappa J region
• Synonyms gene
  • IGKJRB1
  • RBPSUH
• Synonyms gene name
  • recombining binding protein suppressor of hairless (Drosophila)
• Synonyms
  • SUH
  • IGKJRB
  • RBPJK
  • KBF2
  • RBP-J
  • CBF1
• Synonyms name
  • suppressor of hairless homolog (Drosophila)
• GenBank acession
  • L07872
• Locus
  4p15.2
• Discovery year
  1993-04-23
• Entrez gene record
  3516
• Pubmed identfication
  • 8406481
  • 9290259
  • 16354684
• RefSeq identity
  • NM_015874
• Classification
  • PTF1 complex
  • IPT domain containing
• VEGA ID
  OTTHUMG00000097793

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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