RAB8A Antibody

• Catalog number
  R31404
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  RAB8A
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Rab8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Rab8 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P61006
• Purity
  Antigen affinity
• Description
  Ras-related protein Rab8 is a protein that in humans is encoded by the RAB8A gene. The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. Rab8 regulates cilia assembly by targeting and promoting fusion of vesicles near the ciliary membrane. This gene requires CEP290 for centrosome localization and that CEP290 regulates entry of Rab8 into the cilium during assembly of this organelle. It has been shown to interact with Optineurin and MAP4K2.
• Immunogen
  An amino acid sequence from the C-terminus of human Rab8A (KAKMDKKLEGNSPQ) was used as the immunogen for this Rab8 antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the Rab8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RAB8A  
• Gene symbol
  RAB8A
• Short name
  Anti-RAB8A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to RAB8A
• Alternative technique
  antibodies
• Alternative to gene target
  RAB8A, member RAS oncogene family, MEL and RAB8, RAB8A and IDBG-35329 and ENSG00000167461 and 4218, protein kinase binding, nuclei, Rab8a and IDBG-167493 and ENSMUSG00000003037 and 17274, RAB8A and IDBG-642338 and ENSBTAG00000038696 and 100125881

Gene info

• Identity
  HGNC:7007
• Gene
  RAB8A
• Long gene name
  RAB8A, member RAS oncogene family
• Synonyms gene
  • MEL
• Synonyms gene name
  • mel transforming oncogene (derived from cell line NK14)
• Synonyms
  • RAB8
• Locus
  19p13.11
• Discovery year
  1986-01-01
• Entrez gene record
  4218
• Pubmed identfication
  • 1886711
  • 8408203
• RefSeq identity
  • NM_005370
• Classification
  • RAB, member RAS oncogene GTPases
• VEGA ID
  OTTHUMG00000182238

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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