Pyruvate Kinase Antibody

• Catalog number
  F50164-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Pyruvate Kinase
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the Pyruvate Kinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Pyruvate Kinase antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P14618
• Purity
  Purified
• Description
  PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
• Immunogen
  A portion of amino acids 476-505 from the human protein was used as the immunogen for this Pyruvate Kinase antibody.
• Storage
  Aliquot the Pyruvate Kinase antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Pyruvate   Kinase  
• Gene symbol
  PKMP2, PDK4, PDK1P1
• Short name
  Anti-Pyruvate Kinase
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Pyruvate Kinase
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:44244
• Gene
  PKMP2
• Long gene name
  pyruvate kinase M1/2 pseudogene 2
• Synonyms gene name
  • pyruvate kinase, muscle pseudogene 2
• Locus
  Xq12
• Discovery year
  2012-07-25
• Entrez gene record
  402408
• VEGA ID
  OTTHUMG00000021735

Gene info

• Identity
  HGNC:8812
• Gene
  PDK4
• Long gene name
  pyruvate dehydrogenase kinase 4
• Synonyms gene name
  • pyruvate dehydrogenase kinase, isoenzyme 4
  • pyruvate dehydrogenase kinase, isozyme 4
• GenBank acession
  • U54617
• Locus
  7q21.3
• Discovery year
  1996-08-14
• Entrez gene record
  5166
• Pubmed identfication
  • 7499431
• RefSeq identity
  • NM_002612
• VEGA ID
  OTTHUMG00000153977

Gene info

• Identity
  HGNC:49808
• Gene
  PDK1P1
• Long gene name
  pyruvate dehydrogenase kinase 1 pseudogene 1
• Synonyms gene name
  • pyruvate dehydrogenase kinase, isozyme 1 pseudogene 1
• Locus
  9p21.1
• Discovery year
  2014-03-06
• Entrez gene record
  100421194
• RefSeq identity
  • NG_023886

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products