Protein Phosphatase 2A Antibody / PPP2R4
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Catalog number
F53899-0.2ML
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Price
Please ask
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Size
0.2 ml
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Category
Antibody
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Concentration
In 1X PBS, pH 7.4, with 0.09% sodium azide
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
Protein Phosphatase 2A / PPP2R4
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB
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Recommended dilutions
Western blot: 1:1000-2000
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Intented use
This PPP2R4 antibodyis to be used only for research purposes and not for diagnostics..
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Gene ID
5524
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Uniprot
Q15257
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Purity
Antigen affinity
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Description
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine- protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.
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Immunogen
A portion of amino acids 3-35 from the human protein was used as the immunogen for the PPP2R4 antibody.
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Storage
Aliquot the PPP2R4 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
PTPA, LINC01503
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Short name
Anti- Protein Phosphatase 2A / PPP2R4
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit Ig
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Alternative name
Antibodies to Protein Phosphatase 2A / PPP2R4
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Alternative technique
antibodies
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Alternative to gene target
protein phosphatase 2A activator, regulatory subunit 4, PP2A and PR53 and PTPA, PPP2R4 and IDBG-89032 and ENSG00000119383 and 5524, protein phosphatase 2A binding, nuclei, Ppp2r4 and IDBG-156714 and ENSMUSG00000039515 and 110854, PPP2R4 and IDBG-639691 and ENSBTAG00000001933 and 514460
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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