POT1 Antibody

• Catalog number
  R32337
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  POT1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the POT1 antibody should be determined by the researcher.
• Intented use
  This POT1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9NUX5
• Purity
  Antigen affinity
• Description
  Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
• Immunogen
  Amino acids RVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLK of human POT1 were used as the immunogen for the POT1 antibody.
• Storage
  After reconstitution, the POT1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  POT1  
• Gene symbol
  POT1-AS1, POT1
• Short name
  Anti-POT1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to POT1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:49459
• Gene
  POT1-AS1
• Long gene name
  POT1 antisense RNA 1
• GenBank acession
  • BX648695
• Locus
  7q31.33
• Discovery year
  2013-12-05
• Entrez gene record
  401398
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000157170

Gene info

• Identity
  HGNC:17284
• Gene
  POT1
• Long gene name
  protection of telomeres 1
• Synonyms gene name
  • protection of telomeres 1 homolog (S. pombe)
• Synonyms
  • hPot1
  • DKFZp586D211
• GenBank acession
  • AK022580
• Locus
  7q31.33
• Discovery year
  2004-08-20
• Entrez gene record
  25913
• Pubmed identfication
  • 11349150
  • 12391173
• Classification
  • Shelterin complex
• VEGA ID
  OTTHUMG00000157194

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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