Placental Alkaline Phosphatase Antibody

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• Catalog number
  F44307-0.4ML
• Price:

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• Size
  0.4 ml

# #

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Placental Alkaline Phosphatase
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
• Notes
  Titration of the placental Alkaline Phosphatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This placental Alkaline Phosphatase antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P05187
• Purity
  Antigen affinity
• Description
  There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
• Immunogen
  A portion of amino acids 56-83 from the human protein was used as the immunogen for this placental Alkaline Phosphatase antibody.
• Storage
  Aliquot the placental Alkaline Phosphatase antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

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• Gene target
  Placental   Alkaline   Phosphatase  
• Gene symbol
  ALPP, ALPG
• Short name
  Anti-Placental Alkaline Phosphatase
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Label
  Alkaline Phosphatase
• Alternative name
  Antibodies to Placental Alkaline Phosphatase
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:439
• Gene
  ALPP
• Long gene name
  alkaline phosphatase, placental
• Synonyms gene name
  • alkaline phosphatase, placental (Regan isozyme)
• Synonyms
  • PALP
  • PLAP
• Synonyms name
  • Regan isozyme
  • placental alkaline phosphatase
• GenBank acession
  • M14169
• Locus
  2q37.1
• Discovery year
  1986-01-01
• Entrez gene record
  250
• Pubmed identfication
  • 3001717
  • 3461452
• RefSeq identity
  • NM_001632
• Classification
  • Alkaline phosphatases
• VEGA ID
  OTTHUMG00000133255

Gene info

• Identity
  HGNC:441
• Gene
  ALPG
• Long gene name
  alkaline phosphatase, germ cell
• Synonyms gene
  • ALPPL2
• Synonyms gene name
  • alkaline phosphatase, placental like 2
• Synonyms
  • GCAP
• Synonyms name
  • germ cell alkaline phosphatase
• GenBank acession
  • J04948
• Locus
  2q37.1
• Discovery year
  1990-07-06
• Entrez gene record
  251
• RefSeq identity
  • NM_031313
• Classification
  • Alkaline phosphatases
• VEGA ID
  OTTHUMG00000133257

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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