PITX2 Antibody
-
Catalog numberF43713-0.08ML
-
PricePlease ask
-
Size0.08 ml
-
-
CategoryAntibody
-
ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
-
FormAntigen affinity purified
-
ConjugationUnconjugated
-
ClonePolyclonal antibody
-
Recognised antigenPITX2
-
Host animalRabbit (Oryctolagus cuniculus)
-
ClonalityPolyclonal (rabbit origin)
-
Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
-
Tested applicationsWB, IF, ELISA
-
Recommended dilutionsImmunofluorescence: 1:10-1:50,Western blot: 1:1000
-
NotesTitration of the PITX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Intented useThis PITX2 antibodyis to be used only for research purposes and not for diagnostics..
-
UniprotQ99697
-
PurityAntigen affinity
-
DescriptionPilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.
-
ImmunogenA portion of amino acids 122-151 from the human protein was used as the immunogen for this PITX2 antibody.
-
StorageAliquot the PITX2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
-
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolPITX2
-
Short nameAnti-PITX2
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeRabbit Ig
-
Alternative nameAntibodies to PITX2
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namepaired like homeodomain 2
-
Synonyms gene
-
Synonyms gene name
- paired-like homeodomain transcription factor 2
- paired-like homeodomain 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1992-10-05
-
Entrez gene record
-
Pubmed identfication
-
Classification
- PRD class homeoboxes and pseudogenes
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data