PDGFR alpha Antibody
-
Catalog numberF50656-0.4ML
-
PricePlease ask
-
Size0.4 ml
-
-
CategoryAntibody
-
ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
-
FormAntigen affinity purified
-
ConjugationUnconjugated
-
ClonePolyclonal antibody
-
Recognised antigenPDGFR alpha
-
Host animalRabbit (Oryctolagus cuniculus)
-
ClonalityPolyclonal (rabbit origin)
-
Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
-
Tested applicationsWB, IHC, ELISA
-
Recommended dilutionsWestern blot: 1:1000,IHC (Paraffin): 1:10-1:50
-
NotesTitration of the PDGFR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Intented useThis PDGFR alpha antibodyis to be used only for research purposes and not for diagnostics..
-
UniprotP16234
-
PurityAntigen affinity
-
DescriptionPDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
-
ImmunogenA portion of amino acids 740-769 from the human protein was used as the immunogen for this PDGFR alpha antibody.
-
StorageAliquot the PDGFR alpha antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
-
Additional descriptionThe Anti-PDGFR alpha is a α- or alpha protein sometimes glycoprotein present in blood.
-
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolPDGFRB
-
Short nameAnti-PDGFR alpha
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeRabbit Ig
-
Alternative nameAntibodies to PDGFR alpha
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameplatelet derived growth factor receptor beta
-
Synonyms gene
-
Synonyms gene name
- platelet-derived growth factor receptor, beta polypeptide
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
RefSeq identity
-
Classification
- Receptor tyrosine kinases
- CD molecules
- I-set domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data