P2X7 Antibody

• Catalog number
  R31244
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  P2X7
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the P2X7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This P2X7 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q64663
• Purity
  Antigen affinity
• Description
  P2X purinoceptor 7, also called P2X7, is a protein that in humans is encoded by the P2RX7 gene. The product of this gene belongs to the family of purnoceptors for ATP. P2RX7 was mapped to chromosome 12q24 by fluorescence in situ hybridization. It is a receptor for ATP that acts as a ligand-gated ion channel. This gene is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. It could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
• Immunogen
  An amino acid sequence from the N-terminus of rat P2RX7 (MPACCSWNDVFQYETNKVTR) was used as the immunogen for this P2X7 antibody.
• Storage
  After reconstitution, the P2X7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  P2X7  
• Gene symbol
  P2RX7
• Short name
  Anti-P2X7
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to P2X7
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8537
• Gene
  P2RX7
• Long gene name
  purinergic receptor P2X 7
• Synonyms gene name
  • purinergic receptor P2X, ligand-gated ion channel, 7
• Synonyms
  • P2X7
  • MGC20089
• GenBank acession
  • Y09561
• Locus
  12q24.31
• Discovery year
  1997-10-09
• Entrez gene record
  5027
• Pubmed identfication
  • 9038151
  • 9826911
• RefSeq identity
  • NM_002562
• Classification
  • Purinergic receptors P2X
• VEGA ID
  OTTHUMG00000169153

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products