Nucleophosmin Antibody (NPM1)

• Catalog number
  R31031
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Nucleophosmin (NPM1)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P, ICC
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
• Notes
  Variations in secondary/substrate sensitivities and test protocols may require the Nucleophosmin antibody to be titrated for optimal performance.
• Intented use
  This Nucleophosmin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P06748
• Purity
  Antigen affinity
• Description
  Nucleophosmin, also known as NPM, is a protein that in humans is encoded by the NPM1 gene. The gene maps to chromosome 5q35. Nucleophosmin is likely involved in the assembly of ribosomal proteins into ribosomes. An electron microscopic study indicated that Nucleophosmin is concentrated in the granular region of the nucleolus, where ribosome assembly occurs.
• Immunogen
  An amino acid sequence from the N-terminus of human NPM1 (ELKADKDYHFKVDNDENEHQ) was used as the immunogen for this Nucleophosmin antibody (100% homologous in human, mouse and rat).
• Storage
  The lyophilized Nucleophosmin antibody can be stored at 4oC to -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. After reconstitution, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freeze/thaws.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Nucleophosmin   NPM1  
• Gene symbol
  NPM1
• Short name
  Anti-Nucleophosmin (NPM1)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Nucleophosmin (NPM1)
• Alternative technique
  antibodies
• Alternative to gene target
  nucleophosmin (nucleolar phosphoprotein B23, numatrin), B23 and NPM, NPM1 and IDBG-57453 and ENSG00000181163 and 4869, unfolded protein binding, nuclei

Gene info

• Identity
  HGNC:7910
• Gene
  NPM1
• Long gene name
  nucleophosmin 1
• Synonyms gene name
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • nucleophosmin
• Synonyms
  • B23
  • NPM
• Synonyms name
  • nucleolar phosphoprotein B23
  • numatrin
  • nucleophosmin/nucleoplasmin family, member 1
• GenBank acession
  • M26697
• Locus
  5q35.1
• Discovery year
  1993-08-24
• Entrez gene record
  4869
• Pubmed identfication
  • 8471164
  • 8122112
• RefSeq identity
  • NM_002520
• VEGA ID
  OTTHUMG00000130465
• Locus Specific Databases
  • LRG_458

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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