NPM1 Antibody

• Catalog number
  F48247-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  NPM1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IHC, FACS, IF, WB, ELISA
• Recommended dilutions
  Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the NPM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This NPM1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P06748
• Purity
  Purified
• Description
  Nucleophosmin/NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
• Immunogen
  A portion of amino acids 7-33 from the human protein was used as the immunogen for this NPM1 antibody.
• Storage
  Aliquot the NPM1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NPM1  
• Gene symbol
  NPM1
• Short name
  Anti-NPM1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to NPM1
• Alternative technique
  antibodies
• Alternative to gene target
  nucleophosmin (nucleolar phosphoprotein B23, numatrin), B23 and NPM, NPM1 and IDBG-57453 and ENSG00000181163 and 4869, unfolded protein binding, nuclei

Gene info

• Identity
  HGNC:7910
• Gene
  NPM1
• Long gene name
  nucleophosmin 1
• Synonyms gene name
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • nucleophosmin
• Synonyms
  • B23
  • NPM
• Synonyms name
  • nucleolar phosphoprotein B23
  • numatrin
  • nucleophosmin/nucleoplasmin family, member 1
• GenBank acession
  • M26697
• Locus
  5q35.1
• Discovery year
  1993-08-24
• Entrez gene record
  4869
• Pubmed identfication
  • 8471164
  • 8122112
• RefSeq identity
  • NM_002520
• VEGA ID
  OTTHUMG00000130465
• Locus Specific Databases
  • LRG_458

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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