Nod1 Antibody

• Catalog number
  R31707
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Nod1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Nod1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Nod1 antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  10392
• Purity
  Antigen affinity
• Description
  Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. It is a member of NOD-like receptor protein family and is a close relative of Nod2. It recognizes bacterial molecules and stimulates an immune reaction. Nod1 contains a caspase recruitment domain (CARD). This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. Additionally, it has been shown that Nod1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.
• Immunogen
  Human partial recombinant protein (AA 1-160) was used as the immunogen for this Nod1 antibody.
• Storage
  After reconstitution, the Nod1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Nod1  
• Gene symbol
  NOD1
• Short name
  Anti-Nod1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Nod1
• Alternative technique
  antibodies
• Alternative to gene target
  nucleotide-binding oli this GO merization domain containing 1, CARD4 and CLR7.1 and NLRC1, NOD1 and IDBG-11085 and ENSG00000106100 and 10392, CARD domain binding, Plasma membranes, Nod1 and IDBG-149298 and ENSMUSG00000038058 and 107607, NOD1 and IDBG-633439 and ENSBTAG00000038235 and 520275,781426

Gene info

• Identity
  HGNC:16390
• Gene
  NOD1
• Long gene name
  nucleotide binding oligomerization domain containing 1
• Synonyms gene
  • CARD4
• Synonyms gene name
  • caspase recruitment domain family, member 4
• Synonyms
  • NLRC1
  • CLR7.1
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1
  • NLR family, CARD domain containing 1
• GenBank acession
  • AF126484
• Locus
  7p14.3
• Discovery year
  2001-12-11
• Entrez gene record
  10392
• Pubmed identfication
  • 10224040
  • 10329646
• Classification
  • NLR family
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000023923

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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